Our research program is generally focused in three different areas of transport phenomena and tissue engineering and include: 1) pre-vascularization of implantable thick tissues, 2) 3-D microphysiological systems with perfused human capillaries to simulate cardiac and tumor tissue, and 3) tissue remodeling and optical imaging of mechanics and metabolism.
We utilize both experimental and theoretical techniques. The projects involving prevascularization of an implantable tissue and the creation of perfused 3-D human microtissues are multidiscilplinary and involve resources at the Edwards Lifesciences Center for Cardiovascular Technology, active collaborations with Dr. Chris Hughes and Dr. Abe Lee, and use of the Integrated Nanosystems Research Facility. The tissue engineering projects are supported by a fully-equipped modern cell and tissue culture lab, and focuses on the non-invasive (optical) assessment or characterization of micro- and macromechanial properties of tissues. An additional key collaboration is with the Beckman Laser Institute (via Professor Bruce Tromberg and Professor Zhongping Chen) and Laboratory for Fluorescence Dynamics (vis Professor Enrico Gratton) and their world-class optical imaging faciltities including multi-photon microscopy, optical coherence tomography, fluorescent lifetime imaging, and image correlation spectroscopy. We invite you to explore the lab in more details including specific research projects and the quality individuals that make up the lab.
Steve George (PI)